How to Make San Pedro Cactus Powder? ( A Personal Guide)

The preparation of cactus powder is very easy, but also quite laborious. There are several ways to proceed: dried in the sun, peeled, boiled for at least three hours, macerated in rum for three weeks.

 I chose a mixture of all the methods: I cut the cactus into slices and dried them in the sun for several days. When they were completely dry, I cracked them with a hammer. Finally, I spread them out on a baking sheet and left them in a dehydrator for about two days before grinding them into powder in my coffee grinder.

There are many other methods of preparing cactus powder: some people choose to boil it before drying, and others prefer to macerate it in rum for up to three months. The choice is yours!

For the taste, it is absolutely foul. This is also what dissuades me the most from taking it up again. 

Effects: the powder can be used in three different ways. In a cup of boiling water, it is a kind of “tea” which is ideal for detoxifying after a rich meal or for colds. You can also boil water with the powder and drink it simply, it is less tasty but still effective. Finally, you can put the powder in a bottle of water (1 tablespoon per liter) and keep it for later use by shaking it well before each use.

“The effects of San Pedro are very sensitive. Then, if you let go, the mind accompanies the body and they wander together, in a kind of unity or completeness.”

San Pedro Cactus Powder (Trichocereus Pachanoi) Huachuma Wachuma Echinopsis 

 The San Pedro Cactus powder is 100% flesh, with no core, no spines.

 Andean tribes have used San Pedro cactus incense for decision-making, healing, and spiritual guidance. This plant is now being used by modern people all over the world to inspire creative thinking and problem-solving.

Cultivated by the Incas, it was used to treat a broad range of physical, mental, and emotional disorders, as well as people with addictions such as alcoholism. It is also known for its ability to help with personal growth and spiritual connection.

 It has been used quite regularly throughout South America for a long time to enhance life and connect the people to “Pachamama” (Latin term for Mother Earth). In Peru, they used it in ceremonies and rituals as well. However, it wasn’t until the 1960’s that it started to be more popularized as a recreational drug. This was due to its psychedelic properties.

Echinopsis Pachanoi is known by many names throughout South America such as Achuma, Huachuma, Wachuma, Aguacoya, Hahuacollay, Giganton, or Trichocereus Pachanoi.


There are a variety of methods to drink S.P., for example, there are people who consume it raw in a powder form, while others consume it in a glass with juice or water while others make it into a stew.

However, you must include a bit of Lemon juice, as it is Lemon is the key to activating the S.P.

The amount per person of dry green powder varies between a minimum of 14 grams for a smooth ride; about 25 to 35 grams for a moderate intake, and 35 to 50 grams for a powerful visionary trip lasting up to 18 hours.

It is advised to drink with the guidance of a qualified.

Another source of san Pedro cactus powder to purchase: San Pedro Powder for Sale | Buy San Pedro Cactus Powder


What chemical is San Pedro?

Initially, mescaline was isolated from the cactus and was thought to be the primary psychoactive ingredient in it. Later analysis of the plant material found that the concentration of mescaline was high, and that it was accompanied by three other alkaloids: hordenine, lophophine and DMPEA. Mescaline has been demonstrated to act as a non-selective serotonin receptor agonist.

Are All San Pedro Cactus Psychoactive?

Many cacti are known to be psychoactive, containing phenethylamine alkaloids such as mescaline. However, the two main ritualistic (folkloric) genera are Echinopsis, of which the most psychoactive species is the San Pedro cactus (Echinopsis pachanoi, syn. Trichocereus pachanoi), and Lophophora, which contains the sacred peyote cactus (Lophophora williamsii). 

A common misconception is that all San Pedro cacti are psychoactive, when in fact not all species contain mescaline. The same goes for peyote; it’s only one species of a genus that contains many other species that aren’t psychoactive at all.

It’s important to note that there are legal issues surrounding these plants—many countries have made them illegal to possess or cultivate for any purpose. Laws vary by country and even by state within nations; in some cases, possession may be legal but cultivation is not. So make sure before you start experimenting with any cacti in your area!

Is San Pedro Cactus Toxic?

Mescaline is a psychedelic that occurs naturally in a number of cacti, most notably the Peyote and San Pedro cacti. It is also the active ingredient in some traditional “magic” mushrooms, though not all magic mushrooms contain mescaline. Mescaline causes hallucinations and delusions when consumed by humans. It can also cause nausea if consumed with alcohol, which means that you should be careful while consuming alcohol with mescal cactus. The cactus also contains another compound called hordenine, which is thought to contribute to its psychedelic effects by inhibiting an enzyme that breaks down dopamine in the brain.

Anwar Hossain

My name is Anwar Hossain. I am a cactus lover, researcher, and cactus blogger.

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